Search results for "pattern analysi"

Metilazione del DNA in artrite reumatoide

2005

Lo stato di metilazione del DNA genomico e del gene PTHrP è stato valutato con tecniche molecolari e citogenetiche in artrite reumatoide (AR), patologia autoimmune caratterizzata anche da alta incidenza di linfomi e da ipercalcemia per overespressione del gene PTHrP. La metilazione del DNA, infatti, ha un ruolo critico nello sviluppo delle malattie neoplastiche; il gene PTHrP avendo tre promotori uno dei quali contiene un’isola CpG è un buon candidato per la deregolazione da alterato pattern di metilazione locale. Le indagini sulla metilazione genomica, condotte su DNA estratto da sangue periferico di pazienti e di donatori e amplificato in reazioni di Methylation-Sensitive Arbitrarily Prim…

Photoelastic stress pattern analysis using Fourier transform with carrier fringes: influence of quarter-wave plate error

2002

The Fourier transform method, widely applied in photomechanics for the automated analysis of interferometric fringe patterns, has been recently extended to the photoelastic isochromatic fringe patterns analysis. Unfortunately, its use in photoelasticity involves some limitations that have not been completely highlighted in literature. This work deals with the influence of the quarter-wave plate tolerance on the evaluation of the retardation. Both theoretical and experimental analyses have shown that the quarter-wave plate error does not affect the retardation only if the principal stress directions in the model and in the carrier are aligned. In general, instead, the tolerance of the quarte…

Early alterations of the behavioural structure of mice affected by Duchenne muscular dystrophy and tested in open-field

2020

Present study has been carried out to assess whether early alterations of the behavioural structure may be detected in mice affected by Duchenne muscular dystrophy (DMD). To this purpose, both quantitative and T-pattern analysis (TPA) were used to analyse the behaviour of two groups of male, two months old mice, 18 MDX and 18 normal as control, tested in an open-field apparatus. T-pattern analysis is a multivariate technique able to reveal hidden structural features of behaviour and, in particular, its temporal characteristics. As to quantitative analyses, mean durations evidenced a significant increase of Walking, Modified Climbing and Rearing and a significant reduction of Immobile-Sniffi…

Determining seasonality of mussel collection from an early historic Inuit site, Labrador, Canada: Comparing thin-sections with high-resolution stable…

2018

International audience; Stable oxygen isotope (delta O-18) analysis of mussels (Mytilus sp.) from a 16th to mid-18th century Inuit site in southern Labrador, Canada, indicates multiple seasons of shellfish collection, and by proxy, multiple seasons of site occupation. High-resolution delta O-18 sampling of shell permits a precise season of mussel collection since the temperature and freshwater signal of the local water is retained in the shell. Live-collected specimens of Mytilus sp. obtained from Labrador, were analyzed for stable oxygen isotopes and for growth patterns. These data were used to interpret results from the archaeological shells. Growth pattern analysis was conducted to test …

Multivariate approaches to behavioral physiology

2017

Application of multivariate t-pattern analysis in the study of social interactions in rats

2013

A basic tenet in the realm of modern behavioral sciences is that behavior consists of patterns in time. For this reason, investigations of behavior deal with sequences that are not easily perceivable by the unaided observer. This problem calls for improved means of detection, data handling and analysis. This review focuses on the analysis of the temporal structure of behavior carried out by means of a multivariate approach known as T-pattern analysis. Using this technique, recurring sequences of behavioral events, usually hard to detect, can be unveiled and carefully described. T-pattern analysis has been successfully applied in the study of various aspects of human or animal behavior such …

INTRODUCTION

2016

Discovering hidden recurring patterns in observable behavioral processes is an important issue frequently faced by numerous advanced students and researchers across many research areas, such as, for example, psychology, biology, sports, robotics, media, finance, and medicine. As generally, the many powerful methods included in statistical software packages were not developed for this kind of analysis, discovering such patterns has proven a particularly difficult task, due to a lack of (a) adequate formalized models of the kinds of patterns to look for, (b) corresponding detection algorithms, and (c) their implementation in available software. The research described in this book is based on …

Effects of Substantia Nigra pars compacta lesion on the behavioral sequencing in the 6-OHDA model of Parkinson’s disease

2019

The basal ganglia circuitry plays a crucial role in the sequential organization of behavior. Here we studied the behavioral structure of the animals after 21 days of 6-OHDA-induced lesion of the dopaminergic nigrostriatal system. Frequencies and durations of individual components of the behavioral repertoire were calculated; moreover, whether a temporal organization of the activity was present, it was investigated by using T-pattern analysis, a multivariate approach able to detect the real-time sequential organization of behavior. Six sham-depleted and six rats with unilateral 6−OHDA-lesion of the Substantia Nigra pars compacta were used. As to quantitative evaluations, the comparison betwe…

Recurring sequences of multimodal non-verbal and verbal communication during a human psycho-social stress test: A temporal pattern analysis

2020

Abstract Background The Trier Social Stress Test (TSST) is a widely used protocol to study human psycho-social stress responses. Quantitative reports of non-verbal behaviors have been carried out by means of the Ethological Coding System for Interviews (ECSI). However, no data have described whether and how non-verbal and verbal behaviors take part in the composition of multimodal sequences of communication during the test. Method Five non-verbal ECSI categories and four verbal behaviors related with communication were included in the Ethogram. A focal sampling was employed to ensure a high temporal resolution of the behavioral annotation. T-Pattern Analysis was employed to detect statistic…

Prior test experience produces changes of t-patterns spatial distribution in the elevated plus maze test

2014

Aim of present research was to investigate in male Wistar rats whether a prior elevated plus maze experience modifies the temporal structure of the behavioral response following a retest applied after 24h. Video files were coded by means of a software coder and event log files generated for each subject were analyzed by means of a specific software for temporal pattern analysis (Theme). Present research shows a clear reduction of the number of t-patterns from trial one to trial two. This reduction is provoked by the disappearance of t-patterns consisting of behavioral elements occurring in the unprotected zones of the maze. The results suggest that the previous experience in the maze causes…